KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF1C
All Species:
11.52
Human Site:
T418
Identified Species:
18.1
UniProt:
O43896
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43896
NP_006603.2
1103
122947
T418
V
S
P
S
S
P
T
T
H
N
G
E
L
E
P
Chimpanzee
Pan troglodytes
XP_511296
1097
122335
T412
V
S
P
S
S
P
T
T
H
N
G
E
L
E
P
Rhesus Macaque
Macaca mulatta
XP_001117788
1214
134234
T529
V
S
P
S
S
P
T
T
H
N
G
E
L
E
P
Dog
Lupus familis
XP_546571
1191
131317
A505
V
S
P
S
H
P
P
A
H
N
G
E
L
E
P
Cat
Felis silvestris
Mouse
Mus musculus
O35071
1100
122416
P418
A
S
P
S
S
P
P
P
H
N
G
E
L
E
P
Rat
Rattus norvegicus
O35787
1097
122315
P417
A
S
P
S
S
P
P
P
H
N
G
E
L
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509769
1770
199343
Q405
S
S
C
S
L
S
S
Q
V
G
L
T
S
V
T
Chicken
Gallus gallus
XP_417608
1757
197902
Q405
S
S
C
S
L
S
S
Q
V
G
L
T
S
V
S
Frog
Xenopus laevis
Q91784
1226
138905
I488
S
S
G
I
A
G
S
I
E
A
M
D
E
E
A
Zebra Danio
Brachydanio rerio
XP_699380
1180
133432
T417
S
L
P
Y
V
Q
S
T
S
D
A
P
M
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZAJ2
1670
189326
S401
T
K
S
T
V
I
K
S
P
T
K
S
R
N
R
Honey Bee
Apis mellifera
XP_397276
1682
191012
E398
I
V
R
V
V
K
R
E
D
D
V
K
E
T
R
Nematode Worm
Caenorhab. elegans
P23678
1584
179603
H393
V
Q
E
T
P
G
K
H
K
K
G
P
K
L
P
Sea Urchin
Strong. purpuratus
P46872
699
78679
E148
L
V
R
V
S
Y
L
E
I
Y
N
E
E
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
E377
V
Q
V
W
R
G
G
E
T
V
P
K
E
K
W
Conservation
Percent
Protein Identity:
100
99
89.6
87.7
N.A.
94.1
92.7
N.A.
38.1
38.7
23.9
60.4
N.A.
30.7
36.2
30.3
27.6
Protein Similarity:
100
99
89.9
89.3
N.A.
95.5
94.6
N.A.
48.6
48.4
42.3
71.8
N.A.
42.8
47.6
43.5
41
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
13.3
13.3
13.3
20
N.A.
0
0
20
13.3
P-Site Similarity:
100
100
100
80
N.A.
80
80
N.A.
20
20
33.3
40
N.A.
13.3
20
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
7
0
0
7
0
7
7
0
0
0
7
% A
% Cys:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
14
0
7
0
0
0
% D
% Glu:
0
0
7
0
0
0
0
20
7
0
0
47
27
54
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
20
7
0
0
14
47
0
0
0
7
% G
% His:
0
0
0
0
7
0
0
7
40
0
0
0
0
0
0
% H
% Ile:
7
0
0
7
0
7
0
7
7
0
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
7
14
0
7
7
7
14
7
7
7
% K
% Leu:
7
7
0
0
14
0
7
0
0
0
14
0
40
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
40
7
0
0
7
0
% N
% Pro:
0
0
47
0
7
40
20
14
7
0
7
14
0
0
47
% P
% Gln:
0
14
0
0
0
7
0
14
0
0
0
0
0
0
0
% Q
% Arg:
0
0
14
0
7
0
7
0
0
0
0
0
7
0
14
% R
% Ser:
27
60
7
54
40
14
27
7
7
0
0
7
14
0
7
% S
% Thr:
7
0
0
14
0
0
20
27
7
7
0
14
0
7
7
% T
% Val:
40
14
7
14
20
0
0
0
14
7
7
0
0
20
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
7
0
7
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _